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Year : 2012  |  Volume : 2  |  Issue : 1  |  Page : 30-34

Remission in juvenile-onset recurrent respiratory papillomatosis

Department of ENT, Deenanath Mangeshkar Hospital and Research Centre, Pune, Maharashtra, India

Correspondence Address:
Sachin Gandhi
Department of ENT, Deenanath Mangeshkar Hospital and Research Centre, Pune, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2230-9748.94731

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Background: Juvenile-onset recurrent respiratory papillomatosis (JORRP) is a distressing disease due to relentless recurrence and progression. In JORRP, recurrence is a rule, but remission can be considered if the disease-free period after a particular treatment modality is more than one year. Objective : The present study was undertaken with the aim to address this dilemma of remission in JORRP. Materials and Methods: A total of 30 patients of JORRP presenting over 2 years were included. Detailed history, aggressiveness of disease, number of surgical interventions, and surgical modality used were elicited. Videolaryngostroboscopy was performed in all patients using Kays RLS 9100B stroboscope. Papilloma excision was done using CO 2 laser and all patients were followed up three monthly for 1 year, then were kept on yearly follow-up. Results: It was observed that majority of the patients (83%) underwent recurrent excision of papillomas for 1 to 5 times. Of the 30 patients, 15 (50%) showed remission. Eleven of the 30 patients (36.67%) had minimal papillomas and symptomatic recurrence of papilloma was seen in four of the 30 patients (13.33%) and required further surgeries. Nine of the 30 patients who showed remission were diagnosed and managed within 1- to 15-year age group. Six of the 30 patients who presented with recurrence and minimal papillomas were in the age group 31 to 45 years. These patients had transition of JORRP to adult papilloma. Conclusion: The present study shows that the chance of remission is higher in children who had an early onset of JORRP. Remission was more when surgical excision was done only with CO2 laser.

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