Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 328 | Search articles
Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | SubscribeLogin 
     


 
 
Table of Contents
LETTER TO EDITOR
Year : 2018  |  Volume : 8  |  Issue : 2  |  Page : 50

A case of primary mucosa-associated lymphoid tissue lymphoma of the larynx


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication24-Jul-2019

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
P.O. Box 55302, Baghdad Post Office, Baghdad
Iraq
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jlv.JLV_23_18

Rights and Permissions

How to cite this article:
Al-Mendalawi MD. A case of primary mucosa-associated lymphoid tissue lymphoma of the larynx. J Laryngol Voice 2018;8:50

How to cite this URL:
Al-Mendalawi MD. A case of primary mucosa-associated lymphoid tissue lymphoma of the larynx. J Laryngol Voice [serial online] 2018 [cited 2019 Aug 26];8:50. Available from: http://www.laryngologyandvoice.org/text.asp?2018/8/2/50/263375



Sir,

I read with interest the case report by Gandhi et al.[1] on primary mucosa-associated lymphoid tissue (MALT) lymphoma of the larynx in an Indian patient. The authors described nicely the clinical presentation, results of videolaryngostroboscopic examination, findings of histopathological analysis and immunohistochemical staining, and cycles of chemotherapy in the studied patient. I assume that the rarity of the tumor to affect the larynx should alert the authors to consider defective immune status in the studied patient. Among conditions associated with defective immune states, human immunodeficiency virus (HIV) infection is of great importance. My assumption is based on the following point. It is obvious that individuals infected with HIV are more vulnerable to various types of tumors compared to healthy individuals. The increased vulnerability has been suggested to be related to various factors, including low immunity, coinfection with oncogenic viruses, and prolongation of life due to the use of antiretroviral therapy.[2] Among tumors, MALT lymphoma has been reported in HIV-positive patients.[3] To my knowledge, India is one of the Asian countries significantly facing the serious health aftermaths of HIV infection. The available data pointed out to 0.26% HIV seroprevalence compared with a global average of 0.2%.[4] Hence, defining HIV status in the studied patient by the diagnostic panel of blood CD4 lymphocyte count and viral overload estimations was envisaged. If that cluster of tests were to disclose HIV reactivity, the case in question could be surely regarded a novel case report. This is because HIV-associated laryngeal MALT lymphoma has never been reported in the world literature so far.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Gandhi S, Gupta S, Joshi S, Ghosh S. A case of primary mucosa-associated lymphoid tissue lymphoma of the larynx. J Laryngol Voice 2017;7:40-2.  Back to cited text no. 1
  [Full text]  
2.
Valencia Ortega ME. Malignancies and infection due to the human immunodeficiency virus. Are these emerging diseases? Rev Clin Esp 2018;218:149-55.  Back to cited text no. 2
    
3.
Boulanger E, Meignin V, Baia M, Molinier-Frenkel V, Leroy K, Oksenhendler E, et al. Mucosa-associated lymphoid tissue lymphoma in patients with human immunodeficiency virus infection. Br J Haematol 2008;140:470-4.  Back to cited text no. 3
    
4.
Paranjape RS, Challacombe SJ. HIV/AIDS in India: an overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4.  Back to cited text no. 4
    




 

Top
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
    References

 Article Access Statistics
    Viewed38    
    Printed9    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal